A third sex-linked lethal factor in Drosophila

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A female-specific lethal lesion in an X-linked positive regulator of the Drosophila sex determination gene, Sex-lethal.

Characterization of a partial-loss-of-function, female-specific lethal mutation has identified an X-linked genetic element (1-34.3; 10B4) that functions as a positive regulator of Sxl, a central gene controlling sex determination in Drosophila melanogaster. The name, sisterless-a, was chosen both to suggest functional similarities that exist between this gene and another positive regulator of S...

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Vital Genes That Flank Sex-Lethal, an X-Linked Sex-Determining Gene of DROSOPHILA MELANOGASTER.

The X-chromosome:autosome balance in D. melanogaster appears to control both sex determination and dosage compensation through effects on a maternally influenced sex-linked gene called Sex-lethal (Sxl; 1-19.2). To facilitate molecular and genetic analysis of Sxl, we attempted to determine the locations of all ethyl methanesulfonate (EMS)-mutable genes vital to both sexes in the region between 6...

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Sex - Linked Genes in Drosophila

Coincidence. . . . . . . . . . . . .............................. 54 Non-disjunction . . . . . . . . .............................. 55 Gynandromorphs. . . . . . . ............................... 55 Absence of gynandromorp s hybrids.. .................... 60 Somatic mutations, . . . . . ................................... 61 SUMVARY.. ................................................................

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A sex-linked lethal gene in the fowl.

1. The ladykiller (lk) gene has been located on the sex chromosome of the fowl. It is 4.2 map units distant from the feathering rate locus (k) and 11.2 map units distant from the dwarf (dw) locus. 2. Most of the embryonic mortalities associated with this gene occurred between 3 and 4 d of incubation.

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Sex-Linked Lethal Mutations Induced by Thermal Neutrons in Male and Female Drosophila Melanogaster.

HE experiments to be described are concerned with a comparative study of T the mutagenic effectiveness of thermal neutrons in producing sex-linked lethal mutations in male and female Drosophila melanogaster. Some of this work has appeared previously in abstract form (KING 1952a). Preliminary comparative studies of the mutagenic effectiveness of X-rays in producing sex-linked lethal mutations in...

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ژورنال

عنوان ژورنال: Journal of Experimental Zoology

سال: 1914

ISSN: 0022-104X,1097-010X

DOI: 10.1002/jez.1400170302